| dc.description.abstract | Since several decades, minimally-invasive surgery has continuously improved both clinical
workflow and outcome. Such procedures minimize patient trauma, decrease hospital
stay or reduce risk of infection. Next generation robot-assisted interventions promise to
further improve on these advantages while at the same time opening the way to new
surgical applications.
Temporal Bone Surgery and Endovascular Aortic Repair are two examples for such
currently researched approaches, where manual insertion of instruments, subject to a
clinician’s experience and daily performance, could be replaced by a robotic procedure.
In the first, a flexible robot would drill a nonlinear canal through the mastoid, allowing a
surgeon access to the temporal bone’s apex, a target often unreachable without damaging
critical risk structures. For the second example, robotically driven guidewires could
significantly reduce the radiation exposure from fluoroscopy, that is exposed to patients
and surgeons during navigation through the aorta.
These robot-assisted surgeries require preoperative planning consisting of segmentation
of risk structures and computation of nonlinear trajectories for the instruments. While
surgeons could so far rely on preoperative images and a mental 3D model of the anatomy,
these new procedures will make computational assistance inevitable due to the added
complexity from image processing and motion planning. The automation of tiresome and
manually laborious tasks is therefore crucial for successful clinical implementation.
This thesis addresses these issues and presents a preoperative pipeline based on CT images
that automates segmentation and trajectory planning. Major contributions include an
automatic shape regularized segmentation approach for coherent anatomy extraction as
well as an exhaustive trajectory planning step on locally optimized Bézier Splines. It also
introduces thorough in silico experiments that perform functional evaluation on real and
synthetically enlarged datasets. The benefits of the approach are shown on an in house
dataset of otobasis CT scans as well as on two publicly available datasets containing aorta
and heart. | en_US |
